SCHEMBL8765334

SCHEMBL8765334

Ic1ccc2c(c1)C=CC2

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
PNMT P11086 6/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
TDP2 O95551 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766370 0.82 PNMT (0.35) CA1CA2PNMTADRA2AADRA2B
SCHEMBL13782128 0.78 ADRA2A (0.37) PNMTADRA2AADRA2BADRA2CTDP2
SCHEMBL9629684 0.76 CA1 (0.34) CA1CA2
SCHEMBL275807 0.74 CA1 (0.33) CA1CA2
SCHEMBL2730845 0.73 MAPT (0.36) CA1CA2
SCHEMBL2965930 0.73 TRPA1 (0.37) CA1CA2PNMTADRA2AADRA2B
SCHEMBL17068939 0.73 ADRA2A (0.33) CA1CA2ADRA2A
SCHEMBL819543 0.73 ADRA2A (0.33) CA1CA2ADRA2A
SCHEMBL924411 0.73 CA1 (0.32) CA1CA2
SCHEMBL275808 0.73 PBRM1 (0.36) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058812-A Double-active-center metallocene complex and preparation method and application thereof 万华化学集团股份有限公司 2025-05-30 CN disclosed
WO-2023177216-A1 ORGANIC ELECTRIC ELEMENT INCLUDING COMPOUND FOR ORGANIC ELECTRIC ELEMENT, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-09-21 WO disclosed
CN-116332769-A OLED hole transport material based on triptycene skeleton, and preparation method and application thereof 中国科学院化学研究所 2023-06-27 CN disclosed
US-10954178-B1 Synthesis of haloindenes THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2021-03-23 US disclosed
US-10954178-B1 Synthesis of haloindenes THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2021-03-23 US disclosed
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed