Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766910 | 0.89 | HTR2A (0.42) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL8766501 | 0.86 | HTR2A (0.40) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL8767227 | 0.85 | SLC6A4 (0.42) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL8766445 | 0.84 | GRM2 (0.41) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL8766453 | 0.84 | GRM2 (0.41) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL8765866 | 0.84 | GRM2 (0.41) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL8766447 | 0.83 | KDM1A (0.47) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL8766350 | 0.81 | HTR2C (0.45) | HTR2AHTR2CSLC6A3SLC6A2HSD11B1 | |
| SCHEMBL8767257 | 0.80 | SMN1; SMN2 (0.36) | OPRM1KDM4ENPY1R | |
| SCHEMBL8093890 | 0.78 | OPRM1 (0.47) | HTR2AOPRM1OPRL1KDM4ENPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |