Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624284 | 0.85 | LMNA (0.58) | GAALMNAJAK2MAPTDRD2 | |
| SCHEMBL9045649 | 0.82 | GAA (0.82) | GAALMNAJAK2MAPTDRD2 | |
| SCHEMBL27980769 | 0.81 | GAA (0.53) | GAALMNAJAK2MAPTDRD2 | |
| SCHEMBL8766561 | 0.80 | L3MBTL1 (0.40) | LMNAMAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL24011910 | 0.80 | GAA (0.78) | GAALMNAJAK2MAPTDRD2 | |
| SCHEMBL9123832 | 0.80 | GAA (0.78) | GAALMNAJAK2MAPTDRD2 | |
| SCHEMBL27980995 | 0.80 | LMNA (0.51) | GAALMNAJAK2MAPTDRD2 | |
| SCHEMBL27980651 | 0.80 | LMNA (0.51) | GAALMNAJAK2MAPTDRD2 | |
| SCHEMBL29016890 | 0.79 | GAA (0.60) | GAALMNAJAK2MAPTDRD2 | |
| SCHEMBL2839885 | 0.79 | GAA (0.64) | GAALMNAJAK2MAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |