Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 12/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 12/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 11/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766474 | 0.87 | HMGCR (0.42) | ENPP2S1PR1S1PR3S1PR2S1PR4 | |
| SCHEMBL8766028 | 0.82 | LMNA (0.40) | LMNARECQLKDM4EALDH1A1CYP3A4 | |
| SCHEMBL8766469 | 0.80 | LMNA (0.38) | LMNARECQLKDM4EALDH1A1TP53 | |
| SCHEMBL8766614 | 0.80 | GAA (0.49) | LMNARECQLALDH1A1CYP3A4PTGS1 | |
| SCHEMBL8766723 | 0.79 | HMGCR (0.39) | LMNARECQLKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8766637 | 0.78 | CA1 (0.46) | LMNARECQLALDH1A1CYP3A4EGFR | |
| SCHEMBL8766658 | 0.76 | MEN1 (0.46) | S1PR1S1PR3S1PR2S1PR4LMNA | |
| SCHEMBL8766760 | 0.75 | MEN1 (0.45) | S1PR1S1PR3S1PR2S1PR4LMNA | |
| SCHEMBL8766734 | 0.75 | ESRRG (0.41) | LMNARECQLKDM4EALDH1A1TP53 | |
| Methyl Phosphonate SCHEMBL27828909 | 0.74 | GAA (0.49) | ENPP2LMNARECQLALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |