Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766583 | 0.88 | HMGCR (0.43) | HMGCRNR1I2LMNARECQLPTGS1 | |
| SCHEMBL8766637 | 0.88 | CA1 (0.46) | HMGCRNR1I2LMNARECQLMEN1 | |
| SCHEMBL8766028 | 0.84 | LMNA (0.40) | HMGCRNR1I2LMNARECQLPTGS1 | |
| SCHEMBL8766469 | 0.82 | LMNA (0.38) | HMGCRNR1I2LMNARECQLPTGS1 | |
| SCHEMBL8766614 | 0.82 | GAA (0.49) | HMGCRNR1I2LMNARECQLPTGS1 | |
| SCHEMBL8766672 | 0.79 | HMGCR (0.43) | HMGCRNR1I2LMNARECQLMEN1 | |
| SCHEMBL8766735 | 0.79 | ENPP2 (0.46) | LMNARECQLPTGS1PTGS2MEN1 | |
| SCHEMBL8766983 | 0.77 | HMGCR (0.45) | HMGCRNR1I2LMNARECQLPTGS1 | |
| SCHEMBL8767341 | 0.76 | HMGCR (0.43) | HMGCRNR1I2LMNARECQLPTGS1 | |
| SCHEMBL8766961 | 0.75 | GAA (0.39) | HMGCRNR1I2LMNARECQLPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |