Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17743496 | 0.94 | CES2 (0.31) | CES2 | |
| SCHEMBL871697 | 0.82 | CES2 (0.44) | CES2 | |
| SCHEMBL21694102 | 0.80 | CES2 (0.34) | CES2 | |
| SCHEMBL345836 | 0.80 | CES2 (0.31) | CES2 | |
| SCHEMBL7256155 | 0.78 | CES2 (0.39) | CES2 | |
| SCHEMBL3363123 | 0.77 | CES2 (0.32) | CES2 | |
| SCHEMBL6429677 | 0.76 | — | — | |
| SCHEMBL2684216 | 0.76 | — | — | |
| SCHEMBL11243551 | 0.75 | CES2 (0.38) | CES2 | |
| SCHEMBL1936164 | 0.75 | CES2 (0.32) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611367-B1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB (US) | 1997-06-25 | — | — | EP | disclosed |
| EP-0611380-B1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE | BAUSCH & LOMB (US) | 1996-06-19 | — | — | EP | disclosed |
| US-5512205-A | BIOMEDICAL ARTICLES, CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-04-30 | — | — | US | disclosed |
| US-5449729-A | Vinyl monomer and crosslinking agent and acrylates with styrene | BAUSCH & LOMB INCORPORATED (US) | 1995-09-12 | — | — | US | disclosed |
| US-5352714-A | Curing and hydrating an unsaturated oxazolone monomer, a polysiloxane having acrylated end groups and an unsaturated monomer; contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1994-10-04 | — | — | US | disclosed |
| EP-0611367-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. | BAUSCH & LOMB (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0611380-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE. | BAUSCH & LOMB (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0603270-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR MAKING THEM | BAUSCH & LOMB INCORPORATED (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5310779-A | Compatible crosslinkers having vinyl-, acrylic-and/or styrenyl-groups to crosslink incompatible unsaturated addition monomers; contact lens; molding materials | BAUSCH & LOMB INCORPORATED (US) | 1994-05-10 | — | — | US | disclosed |
| WO-1993009155-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | disclosed |
| WO-1993005098-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS | BAUSCH & LOMB INCORPORATED (US) | 1993-03-18 | — | — | WO | disclosed |