Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768529 | 0.81 | KCNA3 (0.50) | KCNA3LTA4HKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11737462 | 0.76 | KCNA3 (0.52) | KCNA3KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11293403 | 0.73 | LTA4H (0.54) | LTA4HKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28368864 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL367062 | 0.73 | LMNA (0.52) | LMNAKMT2A | |
| SCHEMBL11605478 | 0.73 | CYSLTR2 (0.58) | LTA4HALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL17905720 | 0.72 | KDM4E (0.65) | LTA4HKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15016887 | 0.72 | ALOX5 (0.56) | ALDH1A1LMNASMN1; SMN2TSHRCYSLTR2 | |
| SCHEMBL14119424 | 0.71 | TSHR (0.51) | LTA4HKDM4ETSHRCYSLTR2CYSLTR1 | |
| SCHEMBL20225797 | 0.71 | TSHR (0.63) | KDM4EALDH1A1LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |