Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767577 | 0.85 | TDP1 (0.37) | GRM2TDP1 | |
| SCHEMBL8767859 | 0.84 | RARB (0.37) | RAB9ASMN1; SMN2HSD17B10MAPTTDP1 | |
| SCHEMBL8768327 | 0.84 | RARB (0.37) | RAB9ASMN1; SMN2HSD17B10MAPTTDP1 | |
| SCHEMBL8767155 | 0.84 | RARB (0.37) | RAB9ASMN1; SMN2HSD17B10MAPTTDP1 | |
| SCHEMBL8767034 | 0.83 | CYP17A1 (0.42) | RAB9ANPC1CYP11B1CYP11B2TDP1 | |
| SCHEMBL8767558 | 0.82 | RARB (0.43) | RAB9ANPC1CYP11B1CYP11B2TDP1 | |
| SCHEMBL8767578 | 0.81 | HTR1A (0.42) | CYP11B1CYP11B2GRM2L3MBTL1TDP1 | |
| SCHEMBL9137888 | 0.78 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL8518049 | 0.78 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL8517552 | 0.78 | GRM2 (0.45) | RAB9ANPC1SMN1; SMN2TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |