Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135310 | 0.89 | CASP3 (0.40) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL9136119 | 0.86 | CASP3 (0.40) | RAB9ANPC1SMN1; SMN2TP53GRM2 | |
| SCHEMBL9135363 | 0.86 | CYP17A1 (0.35) | RAB9ACYP11B1CYP11B2 | |
| SCHEMBL9138846 | 0.82 | NPC1 (0.42) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL9135501 | 0.81 | NPC1 (0.41) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL9135175 | 0.81 | NPC1 (0.41) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL8767203 | 0.78 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL8517924 | 0.78 | SMN1; SMN2 (0.45) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL8517439 | 0.78 | NPC1 (0.45) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL9313079 | 0.78 | SMN1; SMN2 (0.45) | RAB9ANPC1SMN1; SMN2TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478497-A | For electro-optical purposes | HOFFMANN-LA ROCHE INC. (US) | 1995-12-26 | — | — | US | disclosed |