Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767444 | 0.95 | KMO (0.55) | KMOCYP1A2NPC1RAB9APOLB | |
| SCHEMBL8768108 | 0.83 | KMO (0.65) | KMOCYP1A2NPC1RAB9APOLB | |
| SCHEMBL8768117 | 0.83 | KMO (0.65) | KMOCYP1A2NPC1RAB9APOLB | |
| SCHEMBL8767747 | 0.82 | KMO (0.56) | KMOCYP1A2NPC1RAB9APOLB | |
| SCHEMBL4300707 | 0.79 | NPC1 (0.56) | KMONPC1RAB9APOLBHSD17B10 | |
| SCHEMBL30839555 | 0.74 | CYP1A2 (0.57) | KMOCYP1A2POLBHSD17B10L3MBTL1 | |
| SCHEMBL8767305 | 0.72 | ALDH1A1 (0.39) | NPC1POLBHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL14578731 | 0.71 | KMO (0.60) | KMOCYP1A2NPC1RAB9APOLB | |
| SCHEMBL5946299 | 0.71 | CYP1A2 (0.57) | KMOCYP1A2NPC1RAB9APOLB | |
| SCHEMBL31427168 | 0.70 | KMO (1.00) | KMOCYP1A2POLBHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790241-A1 | COMPLEXONES WITH THE STRUCTURE OF N-2-(AZOL-1(2)-YL)ETHYLIMINODIACETIC ACIDS, SYNTHESIS, ANALYTICAL STUDY AND BIOLOGICAL APPLICATIONS | UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA (ES) | 1997-08-20 | — | — | EP | claimed |
| EP-0790241-A1 | COMPLEXONES WITH THE STRUCTURE OF N-2-(AZOL-1(2)-YL)ETHYLIMINODIACETIC ACIDS, SYNTHESIS, ANALYTICAL STUDY AND BIOLOGICAL APPLICATIONS | UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA (ES) | 1997-08-20 | — | — | EP | disclosed |