SCHEMBL8768108

SCHEMBL8768108

O=C(O)CN(CCn1ncc2ccccc21)CC(=O)O.[NaH].[NaH]

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMO O15229 6/20 0.65
CYP1A2 P05177 1/20 0.48
RECQL P46063 2/20 0.48
DAO P14920 1/20 0.43
POLB P06746 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HSD17B10 Q99714 2/20 0.43
TSHR P16473 3/20 0.41
P2RX7 Q99572 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
ADRA2A P08913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8768117 0.97 KMO (0.65) KMOCYP1A2RECQLDAOPOLB
SCHEMBL8767444 0.89 KMO (0.55) KMOCYP1A2RECQLDAOPOLB
SCHEMBL8767747 0.85 KMO (0.56) KMOCYP1A2RECQLDAOPOLB
SCHEMBL8767289 0.83 KMO (0.53) KMOCYP1A2RECQLDAOPOLB
SCHEMBL324038 0.79 KMO (1.00) KMOCYP1A2RECQLDAOPOLB
SCHEMBL31427168 0.79 KMO (1.00) KMOCYP1A2RECQLDAOPOLB
SCHEMBL22965232 0.77 KMO (0.82) KMOCYP1A2RECQLDAOPOLB
SCHEMBL29544889 0.76 KMO (0.71) KMOCYP1A2RECQLDAOPOLB
SCHEMBL3374171 0.76 KMO (0.71) KMOCYP1A2RECQLDAOPOLB
SCHEMBL30839555 0.74 CYP1A2 (0.57) KMOCYP1A2RECQLDAOPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790241-A1 COMPLEXONES WITH THE STRUCTURE OF N-2-(AZOL-1(2)-YL)ETHYLIMINODIACETIC ACIDS, SYNTHESIS, ANALYTICAL STUDY AND BIOLOGICAL APPLICATIONS UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA (ES) 1997-08-20 EP disclosed