Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768745 | 0.80 | ALOX15 (0.49) | ALOX15MAPTHPNSIRT5VCAM1 | |
| SCHEMBL8768484 | 0.75 | MAPT (0.44) | ALOX15MAPTHPNSIRT5VCAM1 | |
| SCHEMBL10506394 | 0.74 | TSHR (0.44) | ALOX15MAPTHPNSIRT5VCAM1 | |
| SCHEMBL10698130 | 0.71 | ALOX15 (0.63) | ALOX15MAPTHPNSIRT5VCAM1 | |
| SCHEMBL10503818 | 0.71 | ALOX15 (0.63) | ALOX15MAPTHPNSIRT5VCAM1 | |
| SCHEMBL8698598 | 0.71 | PTGS1 (0.49) | ALOX15MAPTHPNSIRT5VCAM1 | |
| SCHEMBL10708262 | 0.71 | MAPT (0.57) | ALOX15MAPTHPNSIRT5VCAM1 | |
| SCHEMBL646923 | 0.70 | ALOX15 (0.61) | ALOX15MAPTHPNSIRT5VCAM1 | |
| SCHEMBL9504462 | 0.70 | ALOX15 (0.61) | ALOX15MAPTHPNSIRT5VCAM1 | |
| SCHEMBL9008246 | 0.69 | ESR1 (0.59) | ALOX15MAPTHPNSIRT5CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621255-B1 | Substituted phenoxy-isobutyric acids and esters | ADIR (FR) | 1997-08-20 | — | — | EP | disclosed |
| EP-0621255-A1 | Substituted phenoxy-isobutyric acids and esters | ADIR ET COMPAGNIE (FR) | 1994-10-26 | — | — | EP | disclosed |