Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767305 | 0.95 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDALOX15MAPK1 | |
| SCHEMBL8768727 | 0.89 | HDAC8 (0.37) | ALDH1A1ALOX15RXFP1USP2HDAC8 | |
| SCHEMBL8767396 | 0.78 | NPSR1 (0.37) | ALDH1A1HPGDALOX15RXFP1MAPT | |
| SCHEMBL8767444 | 0.74 | KMO (0.55) | HSD17B10NPC1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8767402 | 0.73 | LMNA (0.38) | ALDH1A1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL13895808 | 0.72 | KMT2A (0.49) | ALDH1A1RXFP1MAPTHDAC8KDM4E | |
| SCHEMBL28265957 | 0.71 | HTR2A (0.44) | ALDH1A1NPC1IRAK4KMT2A | |
| SCHEMBL1774699 | 0.69 | KDM4E (0.44) | ALDH1A1HSD17B10HPGDHDAC8KDM4E | |
| SCHEMBL2627042 | 0.69 | MAPT (0.47) | ALDH1A1HSD17B10MAPTKDM4EKMT2A | |
| SCHEMBL8767354 | 0.68 | KDM4E (0.51) | ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790241-A1 | COMPLEXONES WITH THE STRUCTURE OF N-2-(AZOL-1(2)-YL)ETHYLIMINODIACETIC ACIDS, SYNTHESIS, ANALYTICAL STUDY AND BIOLOGICAL APPLICATIONS | UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA (ES) | 1997-08-20 | — | — | EP | claimed |
| EP-0790241-A1 | COMPLEXONES WITH THE STRUCTURE OF N-2-(AZOL-1(2)-YL)ETHYLIMINODIACETIC ACIDS, SYNTHESIS, ANALYTICAL STUDY AND BIOLOGICAL APPLICATIONS | UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA (ES) | 1997-08-20 | — | — | EP | disclosed |