SCHEMBL8767352

SCHEMBL8767352

CC(C)(C)c1cc(CCCNN)cc(C(C)(C)C)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.58
KMT2A Q03164 3/20 0.50
GSR P00390 2/20 0.50
ALDH1A1 P00352 7/20 0.47
TSHR P16473 3/20 0.47
LMNA P02545 2/20 0.47
MAPK1 P28482 3/20 0.46
MEN1 O00255 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
BLM P54132 2/20 0.46
ATM Q13315 2/20 0.46
HIF1A Q16665 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
GMNN O75496 1/20 0.46
GABBR2 O75899 1/20 0.46
TP53 P04637 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
NFKB1 P19838 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1355342 0.86 GAA (0.61) GAAKMT2AGSRALDH1A1TSHR
SCHEMBL9184605 0.84 GAA (0.60) GAAKMT2AGSRALDH1A1TSHR
SCHEMBL283499 0.83 ALDH1A1 (0.59) GAAKMT2AGSRALDH1A1TSHR
SCHEMBL8751536 0.83 ALDH1A1 (0.59) GAAKMT2AGSRALDH1A1TSHR
SCHEMBL25990138 0.83 GAA (0.58) GAAKMT2AGSRALDH1A1TSHR
SCHEMBL3952172 0.83 GAA (0.58) GAAKMT2AGSRALDH1A1TSHR
SCHEMBL9179928 0.83 GAA (0.58) GAAKMT2AGSRALDH1A1TSHR
SCHEMBL17588977 0.81 ALDH1A1 (0.57) GAAKMT2AGSRALDH1A1TSHR
SCHEMBL3762751 0.81 ALDH1A1 (0.57) GAAKMT2AGSRALDH1A1TSHR
SCHEMBL18193749 0.81 ALDH1A1 (0.57) GAAKMT2AGSRALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1144236-A Flame retardant insulation compositions having enhanced curability QUANTUM CHEM CORP (US) 1997-03-05 CN claimed
US-20250092225-A1 THERMOPLASTIC POLYURETHANE PRECURSOR, AND THERMOPLASTIC POLYURETHANE, METHOD OF MANUFACTURING THE SAME AND USES OF THE SAME CHITEC TECHNOLOGY CO., LTD. (TW) 2025-03-20 US disclosed
EP-4520773-A1 THERMOPLASTIC POLYURETHANE PRECURSOR, AND THERMOPLASTIC POLYURETHANE AND PREPARATION METHOD THEREFOR AND USE THEREOF Chitec Technology Co., Ltd. (TW) 2025-03-12 EP disclosed
EP-3762441-A1 POLYURETHANE FOAMS BASED ON POLYETHERCARBONATE POLYOLS Covestro Intellectual Property GmbH & Co. KG (DE) 2021-01-13 EP disclosed
WO-2019170590-A1 POLYURETHANE FOAMS BASED ON POLYETHERCARBONATE POLYOLS COVESTRO DEUTSCHLAND AG (DE) 2019-09-12 WO disclosed
EP-0572253-B1 Metallic transmission medium disposed in stabilized plastic insulation AT & T CORP (US) 1997-08-13 EP disclosed
CN-1144236-A Flame retardant insulation compositions having enhanced curability QUANTUM CHEM CORP (US) 1997-03-05 CN disclosed
US-5270486-A Metallic transmission medium disposed in stabilized plastic insulation AT&T BELL LABORATORIES (US) 1993-12-14 US disclosed
EP-0572253-A2 Metallic transmission medium disposed in stabilized plastic insulation AT&T Corp. (US) 1993-12-01 EP disclosed