SCHEMBL1355342

SCHEMBL1355342

CC(C)(C)c1cc(CCCNNCCCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.61
GSR P00390 2/20 0.53
KMT2A Q03164 3/20 0.53
ALDH1A1 P00352 7/20 0.50
TSHR P16473 3/20 0.50
LMNA P02545 2/20 0.50
MAPK1 P28482 3/20 0.49
MEN1 O00255 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
BLM P54132 2/20 0.49
ATM Q13315 2/20 0.49
HIF1A Q16665 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
GMNN O75496 1/20 0.49
GABBR2 O75899 1/20 0.49
TP53 P04637 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALOX15 P16050 1/20 0.49
NFKB1 P19838 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706288 0.90 GAA (0.52) GAAGSRKMT2AALDH1A1TSHR
SCHEMBL9184605 0.87 GAA (0.60) GAAGSRKMT2AALDH1A1TSHR
SCHEMBL8751536 0.86 ALDH1A1 (0.59) GAAGSRKMT2AALDH1A1TSHR
SCHEMBL283499 0.86 ALDH1A1 (0.59) GAAGSRKMT2AALDH1A1TSHR
SCHEMBL25990138 0.86 GAA (0.58) GAAGSRKMT2AALDH1A1TSHR
SCHEMBL3952172 0.86 GAA (0.58) GAAGSRKMT2AALDH1A1TSHR
SCHEMBL8767352 0.86 GAA (0.58) GAAGSRKMT2AALDH1A1TSHR
SCHEMBL9179928 0.86 GAA (0.58) GAAGSRKMT2AALDH1A1TSHR
SCHEMBL18193748 0.84 ALDH1A1 (0.57) GAAGSRKMT2AALDH1A1TSHR
SCHEMBL8751548 0.84 ALDH1A1 (0.57) GAAGSRKMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3762441-B1 POLYURETHANE FOAMS BASED ON POLYETHER CARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-04-13 EP claimed
US-20200399466-A1 POLYURETHANE FOAMS BASED ON POLYETHERCARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2020-12-24 US claimed
EP-3284779-B1 MODIFIED POLYMER COMPOSITION AND STABILIZER MIXTURE FOR MAKING THE SAME FDC LEES CO LTD (TW) 2020-10-07 EP claimed
US-20110277669-A1 Liquid Compositions Of Polymer Additives And Method For Their Preparation INGENIA POLYMERS CORP. (CA) 2011-11-17 US claimed
US-8021585-B2 Liquid compositions of polymer additives and method for their preparation INGENIA POLYMERS CORP. (CA) 2011-09-20 US claimed
EP-2214219-A2 Light-emitting unit, method of manufacturing the same, and a light source device having the light-emitting unit Samsung Electronics Co., Ltd. (KR) 2010-08-04 EP claimed
US-20100187962-A1 LIGHT-EMITTING UNIT, METHOD OF MANUFACTURING THE SAME, AND A LIGHT SOURCE DEVICE HAVING THE LIGHT-EMITTING UNIT SAMSUNG DISPLAY CO., LTD. (KR) 2010-07-29 US claimed
US-7528185-B2 White polyolefin compositions having reduced die drool EQUISTAR CHEMICALS, LP (US) 2009-05-05 US claimed
US-20080029741-A1 Liquid compositions of polymer additives and method for their preparation INGENIA POLYMERS CORP. (CA) 2008-02-07 US claimed
US-20070037905-A1 Low density polyethylene or linear low density polyethylene, mercaptobenzimidazole compound, titanium dioxide or calcium carbonate; exhibit reduced die lip build-up during extrusion EQUISTAR CHEMICALS, LP 2007-02-15 US claimed
WO-2005111138-A1 WHITE POLYOLEFIN COMPOSITIONS HAVING REDUCED DIE DROOL EQUISTAR CHEMICALS, LP (US) 2005-11-24 WO claimed
US-20050256239-A1 White polyolefin compositions having reduced die drool EQUISTAR CHEMICALS, LP 2005-11-17 US claimed
WO-2004037912-A2 FLAME RETARDANT INSULATION COMPOSITION HAVING IMPROVED SCORCH RESISTANCE EQUISTAR CHEMICALS, LP (US) 2004-05-06 WO claimed
US-20040072930-A1 Flame retardant insulation composition having improved scorch resistance EQUISTAR CHEMICALS, LP 2004-04-15 US claimed
US-6197864-B1 ETHYLENE-ALKOXY SILANE COPOLYMER, HALOGENATED ORGANIC COMPOUND, ANTIMONY TRIOXIDE, SILANE CONDENSATION CATALYST AND MAGNESIUM HYDROXIDE EQUISTAR CHEMICALS, LP 2001-03-06 US claimed
EP-0520474-B1 Non-tarnishing flame retardant insulation composition QUANTUM CHEM CORP (US) 1996-08-14 EP claimed
US-5401787-A Moisture curable copolymer of an olefin and a vinylsiloxane, halogenated anhydride, antimony oxide QUANTUM CHEMICAL CORPORATION (US) 1995-03-28 US claimed
US-5256488-A Ethylene-vinyl ester or ethylene-alkyl acrylate copolymer, pentaerythritol thiopropionate, and hindered phenol QUANTUM CHEMICAL CORPORATION (US) 1993-10-26 US claimed
US-5225468-A Crosslinkable insulation of addition polymer, filler, alkoxy silane, crosslinking agent and antioxidant QUANTUM CHEMICAL CORPORATION (US) 1993-07-06 US claimed
EP-0520474-A1 Non-tarnishing flame retardant insulation composition QUANTUM CHEMICAL CORPORATION (US) 1992-12-30 EP claimed