Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 13/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 9/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766495 | 0.89 | ESR1 (0.37) | ESR1ESR2GRM1GRM4ERBB2 | |
| SCHEMBL8766469 | 0.78 | LMNA (0.38) | CYP1A2MEN1KMT2AGAAPOLB | |
| SCHEMBL8766182 | 0.71 | CA12 (0.39) | ESR1ESR2GRM1GRM4ERBB2 | |
| SCHEMBL8766028 | 0.71 | LMNA (0.40) | CYP1A2MEN1KMT2AGAAPOLB | |
| SCHEMBL5903417 | 0.70 | ESR1 (0.61) | ESR1ESR2GRM1GRM4ERBB2 | |
| SCHEMBL8766961 | 0.69 | GAA (0.39) | MEN1KMT2AGAAPOLBLMNA | |
| SCHEMBL8766614 | 0.68 | GAA (0.49) | CYP1A2MEN1KMT2AGAAPOLB | |
| SCHEMBL8766637 | 0.67 | CA1 (0.46) | MEN1KMT2AGAALMNA | |
| SCHEMBL8766723 | 0.65 | HMGCR (0.39) | MEN1KMT2AGAALMNA | |
| SCHEMBL5903671 | 0.65 | ESR1 (0.54) | ESR1ESR2GRM1GRM4ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |