Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986197 | 0.94 | ALDH1A1 (0.53) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL12610716 | 0.89 | ALDH1A1 (0.55) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL8903560 | 0.88 | MCHR1 (0.44) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL8903552 | 0.88 | MCHR1 (0.44) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL9723167 | 0.86 | L3MBTL1 (0.41) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL10008733 | 0.86 | L3MBTL1 (0.41) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL3432906 | 0.85 | ALDH1A1 (0.69) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL307516 | 0.85 | ALDH1A1 (0.69) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL7830929 | 0.85 | ALDH1A1 (0.69) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL1509367 | 0.85 | ALDH1A1 (0.69) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702638-A | FERROELECTRIC LIQUID CRYSTALS MIXTURES HAVING HIGH NEGATIVE VALUES FOR THE DIELECTRIC ANISOTROPY | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |
| EP-0743971-B1 | PHENANTHRIDINE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1997-09-03 | — | — | EP | disclosed |
| US-5648021-A | Phenanthrene derivatives and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |
| EP-0743971-A1 | PHENANTHRIDINE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021227-A1 | PHENANTHRIDINE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-10 | — | — | WO | disclosed |