Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10008733 | 1.00 | L3MBTL1 (0.41) | L3MBTL1GAATDP1THRATHRB | |
| SCHEMBL9723220 | 0.98 | L3MBTL1 (0.42) | L3MBTL1GAATDP1THRATHRB | |
| SCHEMBL17578004 | 0.94 | L3MBTL1 (0.47) | L3MBTL1GAATDP1LMNAMAPT | |
| SCHEMBL30485468 | 0.94 | L3MBTL1 (0.47) | L3MBTL1GAATDP1LMNAMAPT | |
| SCHEMBL9723174 | 0.89 | ALDH1A1 (0.43) | L3MBTL1GAATDP1MEN1LMNA | |
| SCHEMBL8767442 | 0.86 | ALDH1A1 (0.50) | L3MBTL1GAATDP1MEN1NR1I2 | |
| SCHEMBL2544586 | 0.83 | LMNA (0.49) | L3MBTL1GAATDP1LMNAMAPT | |
| SCHEMBL19160763 | 0.83 | NR5A1 (0.50) | L3MBTL1THRATHRBMEN1NR1I2 | |
| SCHEMBL19160557 | 0.83 | NR5A1 (0.50) | L3MBTL1THRATHRBMEN1NR1I2 | |
| SCHEMBL19160350 | 0.83 | NR5A1 (0.50) | L3MBTL1THRATHRBMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087764-A | Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile | Merck Patent Gesellschaft mit beschrankter Hafung (DE) | 1992-02-11 | — | — | US | disclosed |