SCHEMBL8767449

SCHEMBL8767449

Nc1ccc(Oc2ccc(C(c3ccc(Oc4ccc(N)cc4C(F)(F)C(F)(F)F)cc3)(C(F)(F)F)C(F)(F)F)cc2)c(C(F)(F)C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.41
RAB9A P51151 3/20 0.41
MAPT P10636 7/20 0.39
LMNA P02545 1/20 0.39
ATM Q13315 1/20 0.39
ALDH1A1 P00352 5/20 0.37
NPC1 O15118 2/20 0.37
HPGD P15428 2/20 0.37
MAPK1 P28482 1/20 0.37
TSHR P16473 2/20 0.35
GAA P10253 2/20 0.35
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SLC6A4 P31645 2/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9736024 0.90 L3MBTL1 (0.39) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL1228432 0.90 L3MBTL1 (0.46) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL30632212 0.90 L3MBTL1 (0.46) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL9737743 0.89 L3MBTL1 (0.38) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL9737599 0.89 L3MBTL1 (0.38) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL8761229 0.87 RAB9A (0.43) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL9741436 0.85 MAPT (0.39) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL27739374 0.83 L3MBTL1 (0.55) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL26037436 0.82 L3MBTL1 (0.43) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL8762654 0.82 L3MBTL1 (0.43) L3MBTL1RAB9AMAPTLMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449292-B1 Multilayer printed circuit board and production thereof HITACHI LTD (JP) 1997-08-20 EP disclosed
US-5352762-A Fluorine-containing biscyanamide thermosetting resin, heat resistance, adhesion HITACHI, LTD. (JP) 1994-10-04 US disclosed
EP-0449292-A2 Multilayer printed circuit board and production thereof HITACHI, LTD. (JP) 1991-10-02 EP disclosed