SCHEMBL9737743

SCHEMBL9737743

Nc1ccc(Oc2ccc(C(c3ccc(Oc4ccc(N)cc4C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc3)(C(F)(F)F)C(F)(F)F)cc2)c(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.38
RAB9A P51151 3/20 0.38
MAPT P10636 4/20 0.36
LMNA P02545 1/20 0.36
ATM Q13315 1/20 0.36
NPC1 O15118 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
TSHR P16473 2/20 0.32
GLA P06280 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
CYP3A4 P08684 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9737599 1.00 L3MBTL1 (0.38) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL9736024 0.99 L3MBTL1 (0.39) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL8767449 0.89 L3MBTL1 (0.41) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL10413638 0.88 RAB9A (0.36) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL30632212 0.85 L3MBTL1 (0.46) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL1228432 0.85 L3MBTL1 (0.46) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL10414131 0.84 RAB9A (0.37) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL8761229 0.82 RAB9A (0.43) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL9741436 0.80 MAPT (0.39) L3MBTL1RAB9AMAPTLMNAATM
SCHEMBL6447374 0.80 L3MBTL1 (0.50) L3MBTL1RAB9AMAPTLMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089628-A Heat resistance, moisture resistance, low dielectric constants CENTRAL GLASS COMPANY, LIMITED (JP) 1992-02-18 US disclosed