4-Hydroxyhydrocinnamic Acid Methyl Ester

4-Hydroxyhydrocinnamic Acid Methyl Ester

SCHEMBL95254

COC(=O)CCc1ccc(O)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
KDM4E B2RXH2 2/20 0.52
CYP4F2 P78329 2/20 0.52
CYP4A11 Q02928 2/20 0.52
F13A1 P00488 1/20 0.52
ESR1 P03372 2/20 0.50
F2RL1 P55085 1/20 0.50
ESR2 Q92731 1/20 0.50
ADRB2 P07550 1/20 0.49
ADRB1 P08588 1/20 0.49
ESRRB O95718 1/20 0.49
NFKB1 P19838 2/20 0.49
NFKB2 Q00653 2/20 0.49
RELA Q04206 2/20 0.49
CYP19A1 P11511 2/20 0.49
SLC16A3 O15427 1/20 0.49
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL30611554 0.98 HDAC2 (0.51) HDAC2HDAC8MEN1KMT2AKDM4E
4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL8767620 0.93 FFAR1 (0.54) HDAC2HDAC8MEN1KMT2AESR1
SCHEMBL22922181 0.92 CYP4F2 (0.59) KMT2ACYP4F2CYP4A11F2RL1ADRB2
SCHEMBL3469156 0.91 MAPT (0.50) HDAC2HDAC8MEN1KMT2AKDM4E
SCHEMBL8767622 0.90 KMT2A (0.66) HDAC2HDAC8MEN1KMT2AF2RL1
SCHEMBL1863579 0.89 CALM1 (0.55) KDM4ECYP4F2CYP4A11F13A1ESR1
4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL8402039 0.88 FFAR1 (0.61) KDM4EESRRBALDH1A1LMNATDP1
SCHEMBL11509970 0.88 CYP4F2 (0.50) HDAC2HDAC8MEN1KMT2AKDM4E
SCHEMBL2158877 0.87 CALM1 (0.53) KDM4EESR1ALDH1A1LMNATP53
SCHEMBL11720060 0.86 CYP4F2 (0.50) KMT2AKDM4ECYP4F2CYP4A11F2RL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747215-A1 PYRAZOLE DERIVATIVES AS DUAL FUNCTION UREASE AND NITRIFICATION INHIBITOR Sabic Agri-Nutrients Company (SA) 2026-05-27 EP claimed
WO-2026099762-A1 AMINODITHIOCARBAMATE DERIVATIVES AS DUAL FUNCTION UREASE AND NITRIFICATION INHIBITOR SABIC Agri-Nutrients Company (SA) 2026-05-15 WO claimed
CN-122029140-A Pyrazole derivatives as dual function urease and nitrification inhibitors 沙特基础工业公司农业营养素 2026-05-12 CN claimed
EP-4660175-A1 NITRIFICATION INHIBITOR FOR FERTILIZER APPLICATION Sabic Agri-Nutrients Company (SA) 2025-12-10 EP claimed
WO-2025099631-A1 UREASE INHIBITOR FOR FERTILIZER APPLICATION SABIC Agri-Nutrients Company (SA) 2025-05-15 WO claimed
CN-119954554-A Novel synergistic nitrogen fertilizer with inhibitor wrapped by organic material and preparation process thereof 中国科学院南京土壤研究所 2025-05-09 CN claimed
CN-119855797-A Triazolyl carbinols as nitrification inhibitors for fertilizer applications 沙特基础工业公司农业营养素 2025-04-18 CN claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
WO-2025016960-A1 PYRAZOLE DERIVATIVES AS DUAL FUNCTION UREASE AND NITRIFICATION INHIBITOR SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-01-23 WO claimed
CN-118901365-A Method for improving nitrogen fertilizer utilization rate based on synergistic effect of humic acid and biological nitrification inhibitor 中国科学院南京土壤研究所 2024-11-08 CN claimed
US-7183281-B2 Sulfonylquinoxalone derivatives and related compounds as bradykinin antagonists ELAN PHARMACEUTICALS, INC. (US) 2007-02-27 US claimed
US-7074783-B2 Sulfonylbenzodiazepinone acetamides as bradykinin antagonists ELAN PHARMACEUTICALS, INC. (US) 2006-07-11 US claimed
EP-1549622-A1 SULFONYLBENZODIAZEPINONE ACETAMIDES AS BRADYKININ ANTAGONISTS Elian Pharmaceuticals Inc. (US) 2005-07-06 EP claimed
EP-1501807-A1 SULFONYLQUINOXALONE ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ ANTAGONISTS Elan Pharmaceuticals, Inc. (US) 2005-02-02 EP claimed
CN-1181055-C Alanine class compound, its preparing method and use 中国科学院上海药物研究所 2004-12-22 CN claimed
US-20040147520-A1 Sulfonylquinoxalone acetamide derivatives and related compounds as bradykinin antagonists ELAN PHARMACEUTICALS, INC. 2004-07-29 US claimed
US-20040138208-A1 Sulfonylbenzodiazepinone acetamides as bradykinin antagonists ELAN PHARMACEUTICALS, INC. 2004-07-15 US claimed
WO-2004033436-A1 SULFONYLBENZODIAZEPINONE ACETAMIDES AS BRADYKININ ANTAGONISTS ELAN PHARMACEUTICALS INC (US) 2004-04-22 WO claimed
WO-2003093245-A1 SULFONYLQUINOXALONE ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ ANTAGONISTS ELAN PHARMACEUTICALS, INC. (US) 2003-11-13 WO claimed
CN-1431197-A Alanine class compound, its preparing method and use SHANGHAI INST OF MEDICATION CH (CN) 2003-07-23 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147520-A1 Sulfonylquinoxalone acetamide derivatives and related compounds as bradykinin antagonists BDKRB2, BDKRB1, PDXK HDAC2 2184/4885HDAC8 1982/4885MEN1 1916/4885
US-20040138208-A1 Sulfonylbenzodiazepinone acetamides as bradykinin antagonists BDKRB1, BDKRB2, HRH2 HDAC2 894/4885HDAC8 1433/4885MEN1 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.