SCHEMBL8767657

SCHEMBL8767657

Cc1ccc(C(=O)S(=O)(=O)Oc2ccc(O)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
MAPT P10636 3/20 0.44
ALDH1A1 P00352 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ACHE P22303 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
MAOB P27338 2/20 0.41
POLB P06746 1/20 0.41
MAOA P21397 1/20 0.41
STS P08842 3/20 0.41
MMP13 P45452 1/20 0.40
ENPP3 O14638 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779132 0.85 CES2 (0.48) CA1CA2CA9ALDH1A1NPC1
SCHEMBL25074978 0.74 CA1 (0.55) CA1CA2CA9MAPTALDH1A1
SCHEMBL779286 0.74 TDP1 (0.52) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL4908042 0.74 MEN1 (0.69) CA1CA2CA9MAPTALDH1A1
SCHEMBL10876357 0.74 MEN1 (0.69) CA1CA2CA9MAPTALDH1A1
SCHEMBL23781728 0.72 CA1 (0.55) CA1CA2CA9STSPARP10
SCHEMBL14310920 0.72 LMNA (0.61) MAPTALDH1A1NPC1RAB9AACHE
SCHEMBL1129955 0.72 PRSS1 (0.61) CA1CA2CA9MAPTALDH1A1
SCHEMBL223700 0.72 PRSS1 (0.61) CA1CA2CA9MAPTALDH1A1
SCHEMBL9682967 0.72 PRSS1 (0.61) CA1CA2CA9MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0570186-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-08-13 EP disclosed
EP-0570186-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-11-18 EP disclosed