Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557153 | 0.84 | VCAM1 (0.46) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9747677 | 0.84 | EGFR (0.43) | TDP1ALDH1A1CYP3A4SIRT6DTYMK | |
| SCHEMBL267231 | 0.83 | GAA (0.58) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL1186362 | 0.82 | TDP1 (0.52) | TDP1TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL30032292 | 0.82 | MAPT (0.41) | TDP1ALDH1A1MAPK1KMT2ASIRT6 | |
| SCHEMBL1028481 | 0.82 | TDP1 (0.47) | TDP1ALDH1A1SIRT6DTYMKMAPT | |
| SCHEMBL557039 | 0.81 | CASP6 (0.55) | TSHRKMT2AGAADTYMKMAPT | |
| SCHEMBL19782588 | 0.81 | TDP1 (0.48) | TDP1ALDH1A1RECQLMAPK1KMT2A | |
| SCHEMBL557040 | 0.81 | CASP6 (0.55) | TSHRKMT2AGAADTYMKMAPT | |
| SCHEMBL2722007 | 0.80 | VCAM1 (0.56) | TDP1ALDH1A1SIRT6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3058999-A | — | — | None | — | — | JP | disclosed |
| EP-0513863-B1 | Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates | NITTO BOSEKI CO LTD (JP) | 1997-09-03 | — | — | EP | disclosed |
| EP-0513863-A1 | Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates | NITTO BOSEKI CO., LTD. (JP) | 1992-11-19 | — | — | EP | disclosed |
| US-5115099-A | Modified tripeptides as substrates for determination of enzyme activity | NITTO BOSEKI CO., LTD. (JP) | 1992-05-19 | — | — | US | disclosed |
| JP-H0358999-A | PEPTIDE DERIVATIVE AND DETERMINATION OF ENZYME ACTIVITY USING THE SAME | NITTO BOSEKI CO LTD | 1991-03-14 | — | — | JP | disclosed |
| EP-0347734-A2 | Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates | NITTO BOSEKI CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
| JP-H00358999-A | — | — | 0001-01-01 | — | — | JP | disclosed |