Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782588 | 0.85 | TDP1 (0.48) | BACE1SIRT6TDP1ALDH1A1LMNA | |
| SCHEMBL557153 | 0.85 | VCAM1 (0.46) | SIRT6CA12CA1CA2CA9 | |
| SCHEMBL1028520 | 0.84 | TDP1 (0.46) | SIRT6TDP1NPSR1ALDH1A1LMNA | |
| SCHEMBL8767674 | 0.84 | TDP1 (0.47) | SIRT6TDP1DTYMKALDH1A1LMNA | |
| SCHEMBL1028481 | 0.84 | TDP1 (0.47) | SIRT6TDP1DTYMKALDH1A1MAPT | |
| SCHEMBL1186362 | 0.84 | TDP1 (0.52) | TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL30032292 | 0.84 | MAPT (0.41) | SIRT6TDP1DTYMKALDH1A1MAPT | |
| SCHEMBL268199 | 0.83 | CA12 (0.59) | BACE1SIRT6CA12CA1CA2 | |
| SCHEMBL557039 | 0.82 | CASP6 (0.55) | DTYMKLMNAMAPT | |
| SCHEMBL557040 | 0.82 | CASP6 (0.55) | DTYMKLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230046947-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2023-02-16 | — | — | US | disclosed |
| CN-115279416-A | Reactive conjugates | 德彪药业国际股份公司 | 2022-11-01 | — | — | CN | disclosed |
| EP-4069311-A1 | REACTIVE CONJUGATES | Debiopharm Research & Manufacturing SA (CH) | 2022-10-12 | — | — | EP | disclosed |
| CN-110650968-B | Modified nucleosides or nucleotides | 深圳华大智造科技股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| WO-2021110860-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2021-06-10 | — | — | WO | disclosed |
| CN-110650968-A | Modified nucleosides or nucleotides | 深圳华大智造科技有限公司 | 2020-01-03 | — | — | CN | disclosed |
| US-5110723-A | Assay for microorganisms; no surfactant necessary | EASTMAN KODAK COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5037762-A | Determination Of Enzymes, Metabolites Or Living Cells With Quinone Derivatives | EASTMAN KODAK COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| US-4853186-A | Water-compatible reducible compounds and their use in analytical compositions and methods | EASTMAN KODAK COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
| EP-0247848-A2 | Water-compatible reducible compounds and their use in analytical compositions and methods | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230046947-A1 | REACTIVE CONJUGATES | FCGR3B, FCGR1A, FCGR2A | EGFR 12/4885BACE1 1618/4885SIRT6 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.