Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 10/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767593 | 0.84 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL8924339 | 0.84 | GAA (0.52) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8768112 | 0.84 | PPARA (0.56) | LPAR1LPAR5PPARAPPARGPPARD | |
| SCHEMBL8768990 | 0.82 | PPARA (0.50) | LPAR1LPAR5PPARAPPARGPPARD | |
| SCHEMBL8767753 | 0.79 | PPARA (0.62) | LPAR1LPAR5PPARAPPARGPPARD | |
| SCHEMBL8767679 | 0.78 | PPARA (0.59) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8767730 | 0.78 | PPARA (0.46) | LPAR1LPAR5PPARAPPARGPPARD | |
| SCHEMBL8767784 | 0.77 | PPARA (0.61) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8767727 | 0.77 | PPARA (0.61) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8768686 | 0.77 | PPARA (0.61) | PPARAPPARGPPARDHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |