Phenol

Phenol

SCHEMBL8767771

CCCCC(CC)C[Al+2].[O-]c1ccccc1.[O-]c1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
KDM4E B2RXH2 1/20 0.45
CA2 P00918 3/20 0.43
CYP3A4 P08684 2/20 0.43
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 2/20 0.39
TSHR P16473 2/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
MAPK1 P28482 1/20 0.37
HDAC3 O15379 3/20 0.36
HDAC1 Q13547 3/20 0.36
HDAC2 Q92769 3/20 0.36
HDAC8 Q9BY41 3/20 0.36
HDAC6 Q9UBN7 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL8767125 0.83 ALDH1A1 (0.43) ALDH1A1KDM4ECA2CYP3A4TDP1
Phenol SCHEMBL6205221 0.79 BDKRB2 (0.40) ALDH1A1KDM4ECA2CYP3A4MEN1
Phenol SCHEMBL126078 0.79 DNM1 (0.46) ALDH1A1KDM4EPCSK9CNR2
Phenol SCHEMBL4662523 0.77 PCSK9 (0.41) ALDH1A1TDP1TSHRPCSK9
Hydrochloric Acid SCHEMBL9197776 0.76 ALDH1A1 (0.56) ALDH1A1CA2CYP3A4TDP1L3MBTL1
Bromide SCHEMBL27959978 0.76 ALDH1A1 (0.56) ALDH1A1CA2CYP3A4TDP1L3MBTL1
SCHEMBL5897328 0.76
Butyltriphenylphosphonium SCHEMBL4389741 0.74 HIF1A (0.52) ALDH1A1MEN1MAPTKMT2ATSHR
Phenol SCHEMBL149173 0.73 TP53 (0.41) CYP3A4TDP1LMNATSHRPCSK9
Phenol SCHEMBL150151 0.72 TAAR1 (0.34) ALDH1A1CYP3A4TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0314797-B1 OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL IND (JP) 1997-07-02 EP disclosed
US-5206199-A Transition metal compound, aluminoxane, organoaluminum compound narrow weight distribution, high bulk density MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-04-27 US disclosed
US-5122491-A Coordination catalysts; synergistic effect of aluminoxane and organoaluminum compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-06-16 US disclosed
EP-0314797-A1 OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-05-10 EP disclosed