Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767117 | 1.00 | TDP1 (0.40) | TDP1HTR1AHTR1DHTR1BCXCR1 | |
| SCHEMBL8768332 | 1.00 | TDP1 (0.40) | TDP1HTR1AHTR1DHTR1BCXCR1 | |
| SCHEMBL8767576 | 0.88 | HTR1A (0.38) | TDP1HTR1AHTR1DHTR1BCXCR1 | |
| SCHEMBL8767578 | 0.86 | HTR1A (0.42) | TDP1HTR1AHTR1DHTR1BKDM1A | |
| SCHEMBL8767516 | 0.86 | PDE4A (0.37) | TDP1HTR1AHTR1DHTR1BCXCR1 | |
| SCHEMBL8767164 | 0.85 | NFE2L2 (0.44) | TDP1HTR1AHTR1DHTR1BHPGD | |
| SCHEMBL7745489 | 0.84 | NFE2L2 (0.47) | HTR1AHTR1DHTR1BHPGDPTGES | |
| SCHEMBL7751379 | 0.84 | NFE2L2 (0.47) | HTR1AHTR1DHTR1BHPGDPTGES | |
| SCHEMBL8768327 | 0.84 | RARB (0.37) | TDP1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL8767859 | 0.84 | RARB (0.37) | TDP1HPGDRAB9ASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |