Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767787 | 0.86 | HTR1A (0.34) | PDE4APDE4BPDE4CPDE4DHTR1A | |
| SCHEMBL8767790 | 0.86 | TDP1 (0.40) | XDHHTR1AHTR1DHTR1BTDP1 | |
| SCHEMBL8768332 | 0.86 | TDP1 (0.40) | XDHHTR1AHTR1DHTR1BTDP1 | |
| SCHEMBL8767117 | 0.86 | TDP1 (0.40) | XDHHTR1AHTR1DHTR1BTDP1 | |
| SCHEMBL7751458 | 0.82 | S1PR4 (0.37) | HTR1DHTR1BTLR9TLR8TLR7 | |
| SCHEMBL7751463 | 0.82 | S1PR4 (0.37) | HTR1DHTR1BTLR9TLR8TLR7 | |
| SCHEMBL8767576 | 0.81 | HTR1A (0.38) | HTR1AHTR1DHTR1BTDP1CXCR1 | |
| SCHEMBL7745489 | 0.78 | NFE2L2 (0.47) | HTR1AHTR1DHTR1BHPGD | |
| SCHEMBL7751379 | 0.78 | NFE2L2 (0.47) | HTR1AHTR1DHTR1BHPGD | |
| SCHEMBL7751437 | 0.76 | RARB (0.42) | TLR9TLR8TLR7TDP1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168365-A | Cyclopentyl derivatives | ROLIC AG (CH) | 1997-12-24 | — | — | CN | disclosed |
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |