SCHEMBL8767852

SCHEMBL8767852

C=CC(=O)OC(C)c1ccccc1C(C)(C)Cl

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.37
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C19 P33261 2/20 0.32
HTT P42858 1/20 0.31
THRB P10828 1/20 0.31
ELANE P08246 1/20 0.31
TSHR P16473 1/20 0.30
LPAR1 Q92633 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20102166 0.88 HCAR2 (0.39) HCAR2ALDH1A1CYP3A4CYP2C19THRB
SCHEMBL2743763 0.86 HCAR2 (0.37) HCAR2ALDH1A1CYP3A4CYP2C19THRB
Hydrochloric Acid SCHEMBL2470314 0.84 HCAR2 (0.36) HCAR2ALDH1A1CYP3A4CYP2C19THRB
Hydrochloric Acid SCHEMBL28562162 0.82 HCAR2 (0.35) HCAR2ALDH1A1CYP3A4CYP2C19LPAR1
Hydrochloric Acid SCHEMBL5399306 0.79 HCAR2 (0.34) HCAR2CYP2C19THRBTSHR
Hydrochloric Acid SCHEMBL9794907 0.79 HCAR2 (0.40) HCAR2ALDH1A1CYP2C19HTTTHRB
Trifluoromethanesulfonic Acid SCHEMBL16108557 0.77 HCAR2 (0.32) HCAR2
SCHEMBL1906054 0.77 GABRA1 (0.46) HCAR2CYP2C19THRBTSHR
SCHEMBL3684997 0.77 HCAR2 (0.41) HCAR2ALDH1A1CYP2C19THRBTSHR
SCHEMBL8038710 0.76 HCAR2 (0.41) HCAR2ALDH1A1CYP2C19THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382516-A1 CORE-SHELL PARTICLES FOR SUBTERRANEAN OPERATIONS HALLIBURTON ENERGY SERVICES INC (US) 2025-12-18 US disclosed
EP-0183466-B2 Process for the production of a water-soluble polymer dispersion HYMO CORP (JP) 1997-08-20 EP disclosed
EP-0183466-B1 PROCESS FOR THE PRODUCTION OF A WATER-SOLUBLE POLYMER DISPERSION HYMO CORPORATION (JP) 1990-08-29 EP disclosed
EP-0183466-A2 Process for the production of a water-soluble polymer dispersion HYMO CORPORATION (JP) 1986-06-04 EP disclosed