Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200013 | 0.87 | HCAR2 (0.40) | HCAR2ESR1ADRA2AADRA2BADRA2C | |
| SCHEMBL20102169 | 0.84 | ESR1 (0.38) | HCAR2ESR1KDM4EPOLBACP3 | |
| SCHEMBL1906054 | 0.83 | GABRA1 (0.46) | HCAR2POLBTHRBTSHRCYP1A2 | |
| SCHEMBL28268635 | 0.83 | ESR1 (0.37) | HCAR2ESR1KDM4EPOLBACP3 | |
| SCHEMBL16672653 | 0.82 | HCAR2 (0.47) | HCAR2ESR1ADRA2AADRA2BADRA2C | |
| SCHEMBL16672646 | 0.82 | HCAR2 (0.47) | HCAR2ESR1ADRA2AADRA2BADRA2C | |
| SCHEMBL8038710 | 0.82 | HCAR2 (0.41) | HCAR2KDM4ETHRBALDH1A1TSHR | |
| SCHEMBL9819112 | 0.82 | HCAR2 (0.41) | HCAR2POLBTHRBTSHRCYP1A2 | |
| SCHEMBL7189816 | 0.82 | POLB (0.45) | HCAR2KDM4EPOLBTHRBTHRA | |
| SCHEMBL20102165 | 0.81 | HCAR2 (0.39) | HCAR2KDM4ETHRBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080145405-A1 | Providing a clean device comprising a porous polymer core containing an ocular drug in it cavities and covered by a polymer shell permeable for passage of the drug(s); subjecting the device to a supercritical fluid to remove contaminants; sustained release; grafting or injection; vision defects | BAUSCH & LOMB INCORPORATED | 2008-06-19 | — | — | US | claimed |
| US-20070218104-A1 | Rate controlled release of a pharmaceutical agent in a biodegradable device | BAUSCH & LOMB INCORPORATION | 2007-09-20 | — | — | US | claimed |
| US-20070218103-A1 | Rate controlled release of a pharmaceutical agent in a biodegradable device | BAUSCH & LOMB INCORPORATED | 2007-09-20 | — | — | US | claimed |
| US-20020019492-A1 | Method of making high refractive index ophthalmic device materials | NOVARTIS AG (CH) | 2002-02-14 | — | — | US | claimed |
| EP-4267708-B1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | INFINEUM INT LTD (GB) | 2025-07-02 | — | — | EP | disclosed |
| US-12281203-B2 | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2025-04-22 | — | — | US | disclosed |
| US-20240309155-A1 | Thermally Responsive Brush Polymers Having a Copolymer Backbone and Copolymer Arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-09-19 | — | — | US | disclosed |
| EP-4267708-A1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | Infineum International Limited (GB) | 2023-11-01 | — | — | EP | disclosed |
| CN-116981758-A | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | 英菲诺姆国际有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2022136384-A1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | INFINEUM INTERNATIONAL LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |
| EP-2869389-B1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME | MITSUBISHI CHEM CORP (JP) | 2019-11-13 | — | — | EP | disclosed |
| US-10320030-B2 | Nonaqueous electrolyte solution and nonaqueous electrolyte battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2019-06-11 | — | — | US | disclosed |
| US-20080147021-A1 | DRUG DELIVERY DEVICES | BAUSCH & LOMB INCORPORATED | 2008-06-19 | — | — | US | disclosed |
| US-20080002146-A1 | BIOCOMPATIBLE, SURFACE MODIFIED MATERIALS | BAUSCH & LOMB INCORPORATED | 2008-01-03 | — | — | US | disclosed |
| US-20070218104-A1 | Rate controlled release of a pharmaceutical agent in a biodegradable device | BAUSCH & LOMB INCORPORATION | 2007-09-20 | — | — | US | disclosed |
| US-20070218103-A1 | Rate controlled release of a pharmaceutical agent in a biodegradable device | BAUSCH & LOMB INCORPORATED | 2007-09-20 | — | — | US | disclosed |
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5145990-A | Dehydropeptidase, carbapenicillin potentiation | MERCK & CO., INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-4962097-A | IN COMBINATION WITH A CARBAPENEM OR PENEM ANTIBIOTIC | MERCK & CO., INC. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070218104-A1 | Rate controlled release of a pharmaceutical agent in a biodegradable device | IDUA, ACMSD, MLEC | HCAR2 29/4885ESR1 1489/4885ADRA2A 623/4885 |
| US-20070218103-A1 | Rate controlled release of a pharmaceutical agent in a biodegradable device | IDUA, APEH, PAM | HCAR2 48/4885ESR1 1770/4885ADRA2A 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.