Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | GRK6 | P43250 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174369 | 1.00 | NPC1 (0.62) | NPC1MAPK1NOTUMIDH1GRK6 | |
| SCHEMBL12810983 | 0.97 | NPC1 (0.62) | NPC1MAPK1NOTUMIDH1GRK6 | |
| SCHEMBL13030444 | 0.88 | NPC1 (0.77) | NPC1MAPK1NOTUMIDH1KMT2A | |
| SCHEMBL21873281 | 0.87 | MAPK1 (0.52) | NPC1MAPK1NOTUMIDH1KMT2A | |
| SCHEMBL14158152 | 0.86 | NPC1 (0.51) | NPC1MAPK1NOTUMIDH1GRK6 | |
| SCHEMBL21873274 | 0.85 | NPC1 (0.47) | NPC1MAPK1NOTUMIDH1GRK6 | |
| SCHEMBL21873279 | 0.84 | MAPK1 (0.49) | NPC1MAPK1IDH1KMT2AMEN1 | |
| SCHEMBL13658604 | 0.84 | ALDH1A1 (0.51) | NPC1MAPK1KMT2AMEN1MAPT | |
| SCHEMBL8928563 | 0.83 | NPC1 (0.57) | NPC1MAPK1NOTUMIDH1GRK6 | |
| SCHEMBL8769121 | 0.83 | MAPK1 (0.54) | NPC1MAPK1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513980-B1 | DYEING POLYESTER TEXTILE MATERIALS | CLARIANT FINANCE BVI LTD (VG) | 2011-03-23 | — | — | EP | disclosed |
| US-5649980-A | Process for the photochemical and thermal stabilization of undyed and dyed polyester fibre materials | CIBA-GEIGY CORPORATION (US) | 1997-07-22 | — | — | US | disclosed |
| EP-0584044-B1 | Process for photochemical and thermal stabilization of undyed and dyed polyester fibrous materials | CIBA GEIGY AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| EP-0584044-A1 | Process for photochemical and thermal stabilization of undyert and dyert polyester fibrous materials | CIBA-GEIGY AG (CH) | 1994-02-23 | — | — | EP | disclosed |