SCHEMBL21873274

SCHEMBL21873274

COc1ccc(-c2nc(SC)nc(-c3ccc4ccc5cccc6ccc3c4c56)n2)c(O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 5/20 0.47
▸ MAPK1 P28482 2/20 0.47
▸ MEN1 O00255 5/20 0.38
▸ KMT2A Q03164 5/20 0.38
▸ RAB9A P51151 3/20 0.38
▸ PPARG P37231 2/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ RXRA P19793 1/20 0.38
▸ PPARD Q03181 1/20 0.38
▸ PPARA Q07869 1/20 0.38
▸ IDH1 O75874 1/20 0.37
▸ MGAM O43451 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ SI P14410 1/20 0.37
▸ MGAM2 Q2M2H8 1/20 0.37
▸ MAPT P10636 5/20 0.36
▸ TSHR P16473 2/20 0.36
▸ RXFP1 Q9HBX9 2/20 0.36
▸ LMNA P02545 3/20 0.35
▸ ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24431821 0.87 NPC1 (0.50) NPC1MAPK1MEN1KMT2ARAB9A
SCHEMBL30174369 0.85 NPC1 (0.62) NPC1MAPK1MEN1KMT2ARAB9A
SCHEMBL8767871 0.85 NPC1 (0.62) NPC1MAPK1MEN1KMT2ARAB9A
SCHEMBL21873280 0.84 MAPK1 (0.68) MAPK1MEN1KMT2AL3MBTL1MAPT
SCHEMBL21873279 0.83 MAPK1 (0.49) NPC1MAPK1MEN1KMT2ARAB9A
SCHEMBL12810983 0.82 NPC1 (0.62) NPC1MAPK1MEN1KMT2ARAB9A
SCHEMBL21873281 0.81 MAPK1 (0.52) NPC1MAPK1MEN1KMT2ARAB9A
SCHEMBL24431781 0.78 PPARG (0.40) NPC1MEN1KMT2APPARGL3MBTL1
SCHEMBL24431586 0.78 NPC1 (0.39) NPC1MEN1KMT2ARAB9APPARG
SCHEMBL13851810 0.77 HSD17B1 (0.40) MEN1KMT2ARAB9AL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-19 — — US disclosed
WO-2020071695-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS 삼성디스플레이 주식회사 2020-04-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS CRY1, EPHB4, HTR3D NPC1 3676/4885MAPK1 4734/4885MEN1 1937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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