SCHEMBL21873279

SCHEMBL21873279

COc1ccc(-c2nc(SC)nc(-c3cc4c5ccccc5ccc4c4ccccc34)n2)c(O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.49
▸ NPC1 O15118 4/20 0.46
▸ MAPT P10636 5/20 0.39
▸ ALDH1A1 P00352 4/20 0.39
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ CYP11B1 P15538 3/20 0.39
▸ CYP11B2 P19099 3/20 0.39
▸ CYP17A1 P05093 2/20 0.39
▸ HTT P42858 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ MEN1 O00255 6/20 0.39
▸ KMT2A Q03164 6/20 0.39
▸ L3MBTL1 Q9Y468 3/20 0.39
▸ RXFP1 Q9HBX9 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ CYP1A2 P05177 3/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ PHLPP2 Q6ZVD8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21873281 0.92 MAPK1 (0.52) MAPK1NPC1MAPTALDH1A1SMN1; SMN2
SCHEMBL24431822 0.87 NPC1 (0.49) MAPK1NPC1MAPTALDH1A1SMN1; SMN2
SCHEMBL21873276 0.86 MAPK1 (0.68) MAPK1NPC1MAPTALDH1A1SMN1; SMN2
SCHEMBL30174369 0.84 NPC1 (0.62) MAPK1NPC1MAPTALDH1A1SMN1; SMN2
SCHEMBL8767871 0.84 NPC1 (0.62) MAPK1NPC1MAPTALDH1A1SMN1; SMN2
SCHEMBL21873274 0.83 NPC1 (0.47) MAPK1NPC1MAPTALDH1A1SMN1; SMN2
SCHEMBL24432575 0.82 NPC1 (0.44) MAPK1NPC1MAPTALDH1A1SMN1; SMN2
SCHEMBL12810983 0.81 NPC1 (0.62) MAPK1NPC1MAPTALDH1A1SMN1; SMN2
SCHEMBL24431965 0.79 KMT2A (0.39) NPC1MAPTALDH1A1CYP11B1CYP11B2
SCHEMBL24431824 0.78 NPC1 (0.52) MAPK1NPC1MAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-19 — — US disclosed
WO-2020071695-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS 삼성디스플레이 주식회사 2020-04-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS CRY1, EPHB4, HTR3D MAPK1 4734/4885NPC1 3676/4885MAPT 3397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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