Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.46 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767884 | 1.00 | CA1 (0.55) | CA1CA2ACHEADRB3HDAC8 | |
| SCHEMBL7591102 | 0.89 | ACHE (0.55) | CA1CA2ACHEADRB3HDAC8 | |
| SCHEMBL7591096 | 0.89 | ACHE (0.55) | CA1CA2ACHEADRB3HDAC8 | |
| SCHEMBL9443702 | 0.85 | ADRB3 (0.56) | ADRB3POLBNPY5RADRB1 | |
| Hydrochloric Acid SCHEMBL9443699 | 0.85 | ADRB3 (0.56) | ADRB3POLBNPY5RADRB1 | |
| SCHEMBL9443694 | 0.84 | ADRB3 (0.51) | CA1CA2ACHEADRB3POLB | |
| SCHEMBL9443665 | 0.84 | ADRB3 (0.51) | CA1CA2ACHEADRB3POLB | |
| SCHEMBL9443701 | 0.84 | ADRB3 (0.51) | CA1CA2ACHEADRB3POLB | |
| SCHEMBL7405121 | 0.84 | CA1 (0.49) | CA1CA2ACHEHDAC8POLB | |
| SCHEMBL9443720 | 0.82 | ADRB3 (0.57) | CA1CA2ACHEADRB3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |