Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767884 | 0.84 | CA1 (0.55) | CA1CA2ACHETAOK1TAOK3 | |
| SCHEMBL8767895 | 0.84 | CA1 (0.55) | CA1CA2ACHETAOK1TAOK3 | |
| SCHEMBL9443665 | 0.84 | ADRB3 (0.51) | CA1CA2ACHEALDH1A1POLB | |
| SCHEMBL9443694 | 0.84 | ADRB3 (0.51) | CA1CA2ACHEALDH1A1POLB | |
| SCHEMBL9443701 | 0.84 | ADRB3 (0.51) | CA1CA2ACHEALDH1A1POLB | |
| SCHEMBL7406582 | 0.83 | KDM4E (0.42) | KMT2AALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL5679215 | 0.81 | HDAC8 (0.53) | CA1CA2ACHEKMT2AL3MBTL1 | |
| SCHEMBL7035289 | 0.81 | MTNR1A (0.53) | CA1CA2ACHE | |
| SCHEMBL5681677 | 0.81 | MTNR1A (0.53) | CA1CA2ACHE | |
| SCHEMBL8103696 | 0.79 | FAAH (0.48) | ACHEFAAHKDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117910-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0799189-A4 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-17 | — | — | EP | disclosed |
| EP-0799189-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996018602-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-20 | — | — | WO | disclosed |