Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.42 |
| ▸ | PGR | P06401 | 16/20 | 0.42 |
| ▸ | AR | P10275 | 8/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499361 | 0.88 | NR3C1 (0.41) | NR3C1PGRARCYP3A4CYP17A1 | |
| SCHEMBL8768908 | 0.84 | NR3C1 (0.46) | NR3C1PGRARCYP3A4LMNA | |
| SCHEMBL8768257 | 0.84 | PGR (0.46) | NR3C1PGRARCYP3A4LMNA | |
| SCHEMBL8767959 | 0.84 | NR3C1 (0.46) | NR3C1PGRARCYP3A4LMNA | |
| SCHEMBL8767749 | 0.83 | NR3C1 (0.49) | NR3C1PGRARCYP3A4LMNA | |
| SCHEMBL8767722 | 0.82 | PGR (0.48) | NR3C1PGRARCYP3A4LMNA | |
| SCHEMBL8767961 | 0.82 | PGR (0.48) | NR3C1PGRARCYP3A4LMNA | |
| SCHEMBL8768876 | 0.82 | PGR (0.61) | NR3C1PGRARCYP3A4LMNA | |
| SCHEMBL9019827 | 0.80 | NR3C1 (0.59) | NR3C1PGRARCYP3A4LMNA | |
| SCHEMBL8541047 | 0.80 | PGR (0.48) | NR3C1PGRARCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | claimed |
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5426102-A | Antigestagenic, antiandrogenic, antiglucocorticoid, antimineralcorticoid properties | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-20 | — | — | US | disclosed |