Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 16/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 16/20 | 0.61 |
| ▸ | AR | P10275 | 12/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767749 | 0.89 | NR3C1 (0.49) | PGRNR3C1ARCYP3A4CYP2C19 | |
| SCHEMBL8767722 | 0.87 | PGR (0.48) | PGRNR3C1ARCYP3A4CYP2C19 | |
| SCHEMBL8767961 | 0.87 | PGR (0.48) | PGRNR3C1ARCYP3A4CYP2C19 | |
| SCHEMBL8768257 | 0.84 | PGR (0.46) | PGRNR3C1ARCYP3A4CYP2C19 | |
| SCHEMBL8768908 | 0.84 | NR3C1 (0.46) | PGRNR3C1ARCYP3A4CYP2C19 | |
| SCHEMBL8767959 | 0.84 | NR3C1 (0.46) | PGRNR3C1ARCYP3A4CYP2C19 | |
| SCHEMBL8767958 | 0.82 | NR3C1 (0.42) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL9019768 | 0.78 | PGR (0.68) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL9019846 | 0.78 | NR3C1 (0.83) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL18306390 | 0.77 | PGR (0.60) | PGRNR3C1ARCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | claimed |
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5426102-A | Antigestagenic, antiandrogenic, antiglucocorticoid, antimineralcorticoid properties | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-20 | — | — | US | disclosed |