Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663282 | 0.83 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL620074 | 0.78 | POLB (0.66) | ALDH1A1MEN1KMT2AMMP13POLB | |
| SCHEMBL1663183 | 0.73 | POLB (0.57) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL16789660 | 0.72 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2HPGDHTTGSK3B | |
| SCHEMBL15576222 | 0.71 | HDAC1 (0.65) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL23471096 | 0.71 | POLB (0.58) | ALDH1A1SMN1; SMN2MMP13POLBHPGD | |
| SCHEMBL8142775 | 0.71 | POLB (0.58) | ALDH1A1SMN1; SMN2MAPTMMP13POLB | |
| SCHEMBL7571666 | 0.70 | LMNA (0.66) | SMN1; SMN2KMT2APOLBHPGDHDAC3 | |
| SCHEMBL15947374 | 0.70 | — | — | |
| SCHEMBL1665183 | 0.70 | OGG1 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |