Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 13/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 12/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364319 | 0.81 | CDK1 (0.67) | HSP90AB1HSP90AA1CDK1CCNB1CCNE1 | |
| SCHEMBL1672138 | 0.81 | CDK1 (0.62) | HSP90AB1HSP90AA1CYP2C19CDK1CCNB1 | |
| SCHEMBL30052313 | 0.81 | CDK1 (0.62) | HSP90AB1HSP90AA1CYP2C19CDK1CCNB1 | |
| SCHEMBL2153643 | 0.81 | MGMT (0.54) | FLT4KDRCYP2C19CDK1CCNB1 | |
| SCHEMBL2153079 | 0.80 | HDAC6 (0.56) | HSP90AB1HSP90AA1CYP2C19 | |
| SCHEMBL8769186 | 0.79 | FLT4 (0.72) | FLT4KDRCSNK2A2CSNK2A1 | |
| SCHEMBL9388321 | 0.79 | CYP2C19 (0.47) | CYP2C19CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL8781614 | 0.78 | HSP90AB1 (0.47) | HSP90AB1HSP90AA1CYP2C19CDK1CCNB1 | |
| SCHEMBL7745006 | 0.77 | HSP90AB1 (0.51) | HSP90AB1HSP90AA1CYP2C19CDK1CCNB1 | |
| SCHEMBL13037058 | 0.76 | CYP2C19 (0.46) | CYP2C19CDK1CCNB1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |