Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 1/20 | 0.72 |
| ▸ | KDR | P35968 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30377761 | 0.86 | FLT4 (0.62) | FLT4KDRHPGDCSNK2A2CSNK2A1 | |
| SCHEMBL28939516 | 0.83 | FLT4 (0.62) | FLT4KDRHPGDTAAR1EGFR | |
| SCHEMBL1404491 | 0.80 | DAPK1 (0.72) | FLT4KDRHPGDEGFRDAPK1 | |
| SCHEMBL17364335 | 0.80 | ADORA2A (0.60) | FLT4KDRHPGDTAAR1DAPK1 | |
| SCHEMBL8768015 | 0.79 | HSP90AB1 (0.52) | FLT4KDRCSNK2A2CSNK2A1 | |
| SCHEMBL455646 | 0.78 | P2RX7 (0.49) | FLT4KDRCSNK2A2CSNK2A1EGFR | |
| SCHEMBL23885424 | 0.77 | P2RX7 (0.66) | FLT4KDRCSNK2A2CSNK2A1EGFR | |
| SCHEMBL22326733 | 0.77 | ADORA2A (0.62) | FLT4KDRHPGDTAAR1DAPK1 | |
| SCHEMBL1673251 | 0.77 | EGFR (0.70) | KDREGFRALDH1A1ADORA2BADORA2A | |
| SCHEMBL30377640 | 0.77 | ADCY5 (0.57) | FLT4KDRHPGDTAAR1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |