Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.61 |
| ▸ | PPARG | P37231 | 9/20 | 0.61 |
| ▸ | PPARD | Q03181 | 5/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767844 | 0.90 | PPARA (0.58) | PPARAPPARGPPARDSOAT1PSEN1 | |
| SCHEMBL8768666 | 0.89 | PPARA (0.57) | PPARAPPARGPPARDSOAT1PSEN1 | |
| SCHEMBL8768663 | 0.87 | PPARA (0.69) | PPARAPPARGPPARDSOAT1PSEN1 | |
| SCHEMBL8768759 | 0.85 | PPARA (0.53) | PPARAPPARGPPARDSOAT1PSEN1 | |
| SCHEMBL8767784 | 0.84 | PPARA (0.61) | PPARAPPARGPPARDSOAT1MAPT | |
| SCHEMBL8767727 | 0.84 | PPARA (0.61) | PPARAPPARGPPARDSOAT1MAPT | |
| SCHEMBL8925066 | 0.84 | PPARA (0.85) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8768686 | 0.84 | PPARA (0.61) | PPARAPPARGPPARDSOAT1MAPT | |
| SCHEMBL8767679 | 0.83 | PPARA (0.59) | PPARAPPARGPPARDSOAT1MAPT | |
| SCHEMBL8768838 | 0.81 | PPARA (0.48) | PPARAPPARGPPARDSOAT1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |