Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.53 |
| ▸ | PPARG | P37231 | 11/20 | 0.53 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924425 | 0.92 | PPARA (0.44) | PPARAPPARGPPARDSOAT1HDAC3 | |
| SCHEMBL8768938 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDSOAT1HDAC3 | |
| SCHEMBL8767844 | 0.88 | PPARA (0.58) | PPARAPPARGPPARDSOAT1HDAC3 | |
| SCHEMBL9260818 | 0.86 | SOAT1 (0.43) | PPARAPPARGSOAT1HDAC3HDAC1 | |
| SCHEMBL8768086 | 0.85 | PPARA (0.61) | PPARAPPARGPPARDSOAT1PSEN1 | |
| SCHEMBL8925426 | 0.83 | PPARA (0.45) | PPARAPPARGPPARDSOAT1HDAC3 | |
| SCHEMBL8768838 | 0.83 | PPARA (0.48) | PPARAPPARGPPARDSOAT1HDAC3 | |
| SCHEMBL8767768 | 0.82 | PPARA (0.56) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8767784 | 0.80 | PPARA (0.61) | PPARAPPARGPPARDSOAT1HDAC3 | |
| SCHEMBL8767727 | 0.80 | PPARA (0.61) | PPARAPPARGPPARDSOAT1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |