Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258955 | 0.85 | CNR2 (0.53) | CCKBRCNR2HDAC1PTGESLTA4H | |
| SCHEMBL9260018 | 0.81 | HDAC6 (0.47) | CNR2HDAC1PTGESHDAC6HDAC3 | |
| SCHEMBL8767865 | 0.81 | SOAT1 (0.64) | HRH3PPARGPPARDPPARA | |
| SCHEMBL8768869 | 0.81 | PPARA (0.56) | CCKBRCNR2HDAC1HDAC6HDAC3 | |
| SCHEMBL8768812 | 0.81 | PPARA (0.56) | CCKBRCNR2HDAC1HDAC6HDAC3 | |
| SCHEMBL9784546 | 0.78 | SOAT1 (0.50) | CNR2HDAC1ALDH1A1HDAC6HDAC3 | |
| SCHEMBL8768663 | 0.77 | PPARA (0.69) | CNR2HDAC1ALDH1A1HDAC6HDAC3 | |
| SCHEMBL13018713 | 0.77 | HDAC6 (0.67) | CNR2HDAC1ALDH1A1HDAC6HDAC3 | |
| SCHEMBL9784419 | 0.77 | THRB (0.47) | CNR2HDAC1HDAC6 | |
| SCHEMBL10888065 | 0.76 | HDAC6 (0.63) | HDAC1ALDH1A1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |