Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLA1 | P09884 | 2/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346235 | 0.87 | SMN1; SMN2 (0.56) | ADRA2ASMN1; SMN2POLA1CXCR5PRNP | |
| SCHEMBL346945 | 0.85 | ADRA2A (0.48) | ADRA2ASMN1; SMN2POLA1CXCR5PRNP | |
| SCHEMBL346119 | 0.82 | RXRA (0.42) | PPARA | |
| SCHEMBL345843 | 0.80 | ALDH1A1 (0.44) | CA1CA2ACHE | |
| SCHEMBL24439930 | 0.79 | HDAC1 (0.42) | CXCR5NPC1RAB9ANOTUM | |
| SCHEMBL19469553 | 0.78 | SMN1; SMN2 (0.56) | ADRA2ASMN1; SMN2POLA1MTNR1AMTNR1B | |
| SCHEMBL19469571 | 0.78 | SMN1; SMN2 (0.56) | ADRA2ASMN1; SMN2POLA1MTNR1AMTNR1B | |
| SCHEMBL19520534 | 0.78 | SMN1; SMN2 (0.56) | ADRA2ASMN1; SMN2POLA1MTNR1AMTNR1B | |
| SCHEMBL2055543 | 0.76 | IDH1 (0.44) | POLB | |
| SCHEMBL29857016 | 0.76 | IDH1 (0.44) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |
| EP-0579833-A1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992018461-A1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |