Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209509 | 0.75 | HPRT1 (0.44) | HPRT1KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL1866525 | 0.71 | HPRT1 (0.58) | HPRT1HPGDHSD17B10PDE4AADORA2A | |
| SCHEMBL21383159 | 0.70 | HPRT1 (0.48) | HPRT1HPGDALDH1A1 | |
| SCHEMBL25074075 | 0.70 | HPRT1 (0.43) | HPRT1HPGDHSD17B10PDE4AADORA2A | |
| SCHEMBL8768185 | 0.70 | HPRT1 (0.54) | HPRT1KDM4EHSD17B10CYP2D6ALDH1A1 | |
| SCHEMBL7405149 | 0.68 | HPRT1 (0.47) | HPRT1LMNAADORA3ALDH1A1 | |
| SCHEMBL7375871 | 0.68 | HPRT1 (0.58) | HPRT1KDM4EHSD17B10PDE4APDE4B | |
| SCHEMBL7451801 | 0.67 | HPRT1 (0.45) | HPRT1HPGDRAB9ALMNAADORA2A | |
| SCHEMBL23909407 | 0.67 | HPRT1 (0.45) | HPRT1RAB9ALMNAADORA2AALDH1A1 | |
| SCHEMBL2913487 | 0.66 | HPRT1 (0.59) | HPRT1PDE4AADORA2APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002004449-A2 | METHODS FOR TREATMENT OF CONDITIONS AFFECTED BY ACTIVITY OF MULTIDRUG TRANSPORTERS | NEOTHERAPEUTICS, INC. (US) | 2002-01-17 | — | — | WO | disclosed |
| WO-2002004451-A2 | METHODS FOR STIMULATION OF SYNTHESIS OF SYNAPTOPHYSIN IN THE CENTRAL NERVOUS SYSTEM | NEOTHERAPEUTICS, INC. (US) | 2002-01-17 | — | — | WO | disclosed |