Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593487 | 0.90 | LMNA (0.47) | DRD2DRD4DRD3CYP1A2TDP1 | |
| Hydrochloric Acid SCHEMBL11098692 | 0.87 | LMNA (0.44) | DRD2DRD4DRD3CYP1A2TDP1 | |
| SCHEMBL7771305 | 0.87 | LMNA (0.44) | DRD2DRD4DRD3CYP1A2TDP1 | |
| SCHEMBL11550421 | 0.86 | TDP1 (0.41) | TSHRDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL8648037 | 0.85 | LTA4H (0.45) | TSHRTDP1KMT2ALMNAMAOA | |
| SCHEMBL10860055 | 0.85 | LTA4H (0.45) | TSHRTDP1KMT2ALMNAMAOA | |
| SCHEMBL13289 | 0.84 | LTA4H (0.50) | TSHRTDP1KMT2ACYP3A4LMNA | |
| SCHEMBL11875556 | 0.82 | LTA4H (0.43) | TSHRTDP1KMT2ALMNAMAOA | |
| SCHEMBL8646529 | 0.82 | LTA4H (0.43) | TSHRTDP1KMT2ALMNAMAOA | |
| SCHEMBL8662152 | 0.82 | LTA4H (0.47) | TSHRTDP1KMT2ACYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306094-B1 | PROCESS FOR THE HYDROFORMYLATION OF CERTAIN ACRYLIC ACID DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-01-29 | — | — | EP | claimed |
| EP-0306094-A2 | Process for the hydroformylation of certain acrylic acid derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-03-08 | — | — | EP | claimed |
| EP-0791616-A1 | Process for producing polysuccinimide and use of said compound | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-08-27 | — | — | EP | disclosed |
| EP-0306094-B1 | PROCESS FOR THE HYDROFORMYLATION OF CERTAIN ACRYLIC ACID DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-01-29 | — | — | EP | disclosed |
| EP-0306094-A2 | Process for the hydroformylation of certain acrylic acid derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-03-08 | — | — | EP | disclosed |