Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593487 | 0.97 | LMNA (0.47) | LMNACYP2A6MAOBMAOAMEN1 | |
| Hydrochloric Acid SCHEMBL11098692 | 0.94 | LMNA (0.44) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL8768246 | 0.87 | TSHR (0.46) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL11470964 | 0.84 | LMNA (0.40) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL10491036 | 0.82 | HPGD (0.41) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL11048181 | 0.78 | LMNA (0.44) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL10889093 | 0.77 | HTR2A (0.39) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL5503603 | 0.76 | LMNA (0.42) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL594537 | 0.76 | LMNA (0.42) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL4809479 | 0.74 | ACHE (0.52) | LMNACYP2A6MEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417325-B1 | PROCESS FOR PRODUCING NORCAMPHANEDICARBONITRILES | MITSUI CHEMICALS INC (JP) | 2001-07-11 | — | — | EP | claimed |
| US-5169971-A | Hydrocyanation; zero-valent nickel complex catalyst and a lewis acid; efficient; high selectivity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-12-08 | — | — | US | claimed |
| EP-0417325-A1 | PROCESS FOR PRODUCING NORCAMPHANEDICARBONITRILES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-03-20 | — | — | EP | claimed |
| EP-0438638-B1 | Process for producing norcamphane dicarbonitriles | MITSUI CHEMICALS INC (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-5087722-A | Catalytic hydrocyanation of bicyclo(2.2.1)-5-heptene-2-carbonitrile | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0438638-A1 | Process for producing norcamphane dicarbonitriles | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-07-31 | — | — | EP | disclosed |