Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280569 | 0.80 | CYP1A2 (0.53) | CYP1A2TSHREGFRALDH1A1SMN1; SMN2 | |
| SCHEMBL7280561 | 0.80 | CYP1A2 (0.53) | CYP1A2TSHREGFRALDH1A1SMN1; SMN2 | |
| SCHEMBL23228237 | 0.80 | CYP1A2 (0.72) | CYP1A2TSHRSMN1; SMN2MAPK1TP53 | |
| SCHEMBL455646 | 0.78 | P2RX7 (0.49) | FLT4KDREGFRALDH1A1CSNK2A2 | |
| SCHEMBL1673251 | 0.77 | EGFR (0.70) | KDREGFRALDH1A1ADORA2B | |
| SCHEMBL23885424 | 0.77 | P2RX7 (0.66) | FLT4KDREGFRALDH1A1CSNK2A2 | |
| SCHEMBL8769186 | 0.77 | FLT4 (0.72) | FLT4KDREGFRALDH1A1CSNK2A2 | |
| SCHEMBL8466930 | 0.74 | CYP1A2 (0.72) | CYP1A2TSHRALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL9583631 | 0.72 | CYP1A2 (0.48) | CYP1A2TSHRFLT4KDRALDH1A1 | |
| SCHEMBL9583305 | 0.72 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |