Sugi Predict

Sugi Predict / Compounds / SCHEMBL8768302

SCHEMBL8768302

SCHEMBL8768302

CC#Cc1ccccc1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 3/20 0.52
▸ CA2 P00918 3/20 0.52
▸ CA7 P43166 2/20 0.52
▸ CA9 Q16790 2/20 0.52
▸ CA12 O43570 1/20 0.52
▸ CA4 P22748 1/20 0.52
▸ CA14 Q9ULX7 1/20 0.52
▸ GRM5 P41594 1/20 0.49
▸ ALDH1A1 P00352 4/20 0.48
▸ ADRA2B P18089 1/20 0.48
▸ PTGS1 P23219 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ L3MBTL1 Q9Y468 3/20 0.44
▸ MAPK1 P28482 2/20 0.44
▸ MAPT P10636 1/20 0.44
▸ FFAR1 O14842 1/20 0.44
▸ TP53 P04637 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30022461 0.88 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL4214499 0.88 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL29151787 0.84 POLB (0.41) CA1CA2CA7CA9CA12
SCHEMBL21339755 0.84 APP (0.46) CA1CA2CA7CA9CA12
SCHEMBL10570482 0.80 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL8975682 0.80 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL29031247 0.80 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL29984649 0.78 ALDH1A1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL14997690 0.78 GRM5 (0.54) CA1CA2CA7CA9CA12
SCHEMBL2774016 0.78 FFAR1 (0.60) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3688124-B1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-25 — — EP claimed
CN-110372653-B Selenylation benzofuran compound and synthesis method thereof 温州大学 2022-11-15 — — CN claimed
CN-110791775-B Method for continuously preparing 2-aryl-benzothiophene/furan compounds by using electrochemical microchannel reaction device 南京工业大学 2021-02-05 — — CN claimed
CN-110760877-B Method for continuously preparing 2-aryl-3-halogenated-benzofuran compound by using electrochemical microchannel reaction device 南京工业大学 2021-01-29 — — CN claimed
CN-110791775-A Method for continuously preparing 2-aryl-benzothiophene/furan compounds by using electrochemical microchannel reaction device 南京工业大学 2020-02-14 — — CN claimed
CN-110760877-A Method for continuously preparing 2-aryl-3-halogenated-benzofuran compound by using electrochemical microchannel reaction device 南京工业大学 2020-02-07 — — CN claimed
US-20250236621-A1 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES ENLIVEN INC. 2025-07-24 — — US disclosed
US-12240846-B2 5- and 6-azaindole compounds for inhibition of Bcr-Abl tyrosine kinases ENLIVEN INC. (US) 2025-03-04 — — US disclosed
CN-119019388-A 5-And 6-azaindole compounds for inhibiting Bcr-Abl tyrosine kinase 英莱汶公司 2024-11-26 — — CN disclosed
CN-115052860-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-06-21 — — CN disclosed
US-20230382907-A1 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES ENLIVEN INC. 2023-11-30 — — US disclosed
US-20230382907-A1 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES ENLIVEN INC. 2023-11-30 — — US disclosed
US-20230382907-A1 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES ENLIVEN INC. 2023-11-30 — — US disclosed
WO-2010136475-A1 SUBSTITUTED QUINAZOLINES AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-12-02 — — WO disclosed
US-7691785-B2 Pyridine-3-ketone compound; plant growth controllers SYNGENTA CROP PROTECTION, INC. (US) 2010-04-06 — — US disclosed
US-7488824-B2 Process for the production of substituted nicotinic acid esters SYNGENTA CROP PROTECTION, INC. (US) 2009-02-10 — — US disclosed
EP-1601653-B1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED NICOTINIC ACID ESTERS SYNGENTA PARTICIPATIONS AG (CH) 2009-02-04 — — EP disclosed
US-20080274891-A1 SUBSTITUTED PYRIDINE HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2008-11-06 — — US disclosed
US-7378375-B1 Substituted pyridine herbicides SYNGENTA CROP PROTECTION, INC. (US) 2008-05-27 — — US disclosed
US-7173033-B2 Nitrogen-containing heterocyclic compound ASTELLAS PHARMA INC. (JP) 2007-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250236621-A1 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES ABL1, ABL2, BCR CA1 4735/4885CA2 4223/4885CA7 3708/4885
US-20080274891-A1 SUBSTITUTED PYRIDINE HERBICIDES DDT, CYP1A1, CYP1B1 CA1 1214/4885CA2 687/4885CA7 1553/4885
US-20230382907-A1 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES ABL1, ABL2, BCR CA1 4735/4885CA2 4223/4885CA7 3708/4885
US-12240846-B2 5- and 6-azaindole compounds for inhibition of Bcr-Abl tyrosine kinases ABL1, ABL2, BCR CA1 4735/4885CA2 4223/4885CA7 3708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.