SCHEMBL8975682

SCHEMBL8975682

COC#Cc1ccccc1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA12 O43570 1/20 0.50
CA4 P22748 1/20 0.50
CA14 Q9ULX7 1/20 0.50
GRM5 P41594 1/20 0.47
ALDH1A1 P00352 3/20 0.46
ADRA2B P18089 1/20 0.46
PTGS1 P23219 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
FFAR1 O14842 1/20 0.43
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30022461 0.86 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL4214499 0.86 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL9799731 0.84 CA4 (0.35) CA1CA2CA7CA9CA12
SCHEMBL3950311 0.82 SMN1; SMN2 (0.42) CA1CA2CA7CA9CA12
SCHEMBL5027103 0.80 IRAK4 (0.40) CA1CA2CA7CA9CA12
SCHEMBL8768302 0.80 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL29031247 0.78 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL10570482 0.78 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL1420532 0.77 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL29984649 0.77 ALDH1A1 (0.61) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396313-A Alkenyl borate, and preparation method and application thereof 中山大学 2023-07-07 CN claimed
CN-103951685-A New beta-diketone rare earth organic complex and its preparation method UNIV HUIZHOU 2014-07-30 CN claimed
EP-0543919-B1 USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES SEARLE & CO (US) 1996-04-10 EP claimed
EP-0034743-B1 BENZOXAZOLES, THEIR PREPARATION AND THEIR USE AS MEDICINES Dr. Karl Thomae GmbH (DE) 1984-05-30 EP claimed
CN-115583874-B Method for catalyzing asymmetric tandem reaction of internal alkyne by rhodium metal 南京林业大学 2024-05-28 CN disclosed
CN-114181028-B Preparation method of phenylacetylene 山东博苑医药化学股份有限公司 2023-10-24 CN disclosed
CN-116396313-A Alkenyl borate, and preparation method and application thereof 中山大学 2023-07-07 CN disclosed
CN-115583874-A Method for catalyzing asymmetric series reaction of internal alkyne by using metal rhodium 南京林业大学 2023-01-10 CN disclosed
CN-114181028-A Preparation method of phenylacetylene 山东博苑医药化学股份有限公司 2022-03-15 CN disclosed
CN-112079776-A Light-induced crystallized isoquinoline salt compound, preparation method and application thereof, and preparation method of nanocrystal 华南理工大学 2020-12-15 CN disclosed
CN-103951685-A New beta-diketone rare earth organic complex and its preparation method UNIV HUIZHOU 2014-07-30 CN disclosed